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Medicine

Therapeutic Drug Monitoring of Biologics in Inflammatory Bowel Disease

Quick fact

Up to 30-40% of patients on biologic therapy for IBD fail to achieve or maintain a response, and many have subtherapeutic drug levels or develop anti-drug antibodies that can be detected and managed with therapeutic drug monitoring.

Why this is interesting

Why does a drug that works wonders for one patient with Crohn's disease do nothing for another—even at the same dose? The answer lies not in the drug itself, but in how the body handles it.