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Medicine

Antithrombotic Management in Patients with Mechanical Heart Valves

Quick fact

Even with optimal warfarin therapy, mechanical heart valves carry an annual risk of major thromboembolism of about 1-2%—but if the INR drops below the target range, the risk can skyrocket to over 10% per year.

Why this is interesting

You've just had a metal heart valve installed—but the real challenge begins now: balancing a stroke prevention drug that can also cause dangerous bleeding. How do doctors decide the perfect dose?