Medicine
Comparative Effectiveness of DOACs vs. Warfarin in Atrial Fibrillation
Quick fact
In large trials, DOACs like apixaban and dabigatran reduced stroke risk by about 19–35% compared to warfarin, while also lowering the risk of major bleeding—the very complication doctors tried to avoid.
Why this is interesting
For decades, warfarin was the go-to blood thinner, but now doctors often choose newer pills called DOACs. Why did the gold standard change?