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Medicine

Methotrexate Toxicity and Leucovorin Rescue Protocols

Quick fact

Leucovorin is not a vitamin supplement; it's a drug that bypasses a blocked metabolic step. When given at the right time after methotrexate, it can prevent life-threatening bone marrow suppression.

Why this is interesting

You've heard of chemotherapy, but what if I told you that a key cancer drug can be deadly to healthy cells unless you 'rescue' them with a vitamin-like pill? How do doctors manage to use such a double-edged sword?