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Medicine

Pharmacogenomic-Guided Dosing of Warfarin in Diverse Populations

Quick fact

Genetic variants in CYP2C9 and VKORC1 can account for up to 40% of the variability in warfarin dose requirements, yet almost all dosing algorithms were developed using predominantly European populations, making them less accurate for African and Asian patients.

Why this is interesting

Warfarin, a blood thinner used for decades, still requires careful guesswork to dose safely. What if your DNA could help predict the right dose?

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Pharmacogenomic-Guided Dosing of Warfarin in Diverse Populations

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