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Medicine

Pharmacogenomic Testing for Clopidogrel Metabolism Variants

Quick fact

About 2-14% of people carry two nonfunctional copies of the CYP2C19 gene, making them 'poor metabolizers' who cannot effectively activate clopidogrel, leaving them at higher risk for blood clots.

Why this is interesting

You take a pill to prevent a heart attack, but for some people, that pill never becomes active—and they might never know. Why does the same drug work differently in different people?