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Medicine

Alcoholic Hepatitis Scoring Systems and Therapeutic Options

Quick fact

The Maddrey discriminant function (DF) was the first widely used score: a DF above 32 identifies severe alcoholic hepatitis and is associated with a 30-day mortality of about 30-40% without treatment, and it is the threshold used to consider corticosteroids.

Why this is interesting

A patient with alcoholic hepatitis can appear stable, yet their liver may be failing rapidly. How do clinicians decide who needs urgent treatment and who might recover on their own?