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Chemistry

How DFT Calculations Predict the Energetics of Catalytic Intermediates

Quick fact

DFT calculations can predict the relative stability of catalytic intermediates to within a few kilocalories per mole, often matching experimental measurements closely enough to guide the design of new catalysts.

Why this is interesting

What if you could see the invisible steps of a catalytic reaction before they even happen in the lab? That's exactly what DFT calculations offer chemists—a peek into the energy landscape of catalysis.