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Chemistry

Computational Prediction of Reaction Pathways Using Density Functional Theory

Quick fact

DFT can locate transition states—the fleeting, high-energy configurations that determine reaction rates—with accuracies often within a few kilocalories per mole, enabling the design of catalysts before any experimental synthesis.

Why this is interesting

Imagine being able to watch a chemical reaction unfold at the level of individual electrons, without ever touching a test tube. Density functional theory (DFT) makes this possible, allowing chemists to predict reaction pathways with remarkable accuracy.