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Chemistry

The Role of Cytochrome P450 in Drug and Toxin Metabolism

Quick fact

Your body has a team of enzymes called cytochrome P450 that can oxidize almost any lipophilic chemical—from caffeine to pollutants—making it more water-soluble for excretion. Genetic variations in these enzymes cause up to 10-fold differences in drug clearance between individuals.

Why this is interesting

You swallow a pill, and within hours it’s mostly gone from your body. But how does your body know exactly what to do with a molecule it has never seen before?

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The Role of Cytochrome P450 in Drug and Toxin Metabolism

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