Saved on this device

Follow your curiosity

What discovery has been shared with you?

FACTREE gives you something interesting to discover every day — and something worth talking about together.

Start with one fact. Explore it, go deeper, then follow whichever branch catches your imagination.

Choose subjects for a surprise

Exploring any topic

Begin your discovery

Your next discovery is one click away.

Choose one or more subjects above, or leave Any Topic selected and let curiosity decide.

Medicine

Epigenetic Regulation of Drug-Metabolizing Enzymes in Cancer Therapy

Quick fact

Tumors can switch off genes for drug-metabolizing enzymes through DNA methylation or histone modifications, making them resistant to chemotherapy, yet this process is reversible—unlike genetic mutations—offering a target for new drugs.

Why this is interesting

You might assume that your genes are fixed, but your cells can turn drug-processing enzymes on or off without changing the DNA code. How could this affect whether a cancer drug works or harms you?