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Biology

DNA Methylation Patterns in Cancer Epigenetics

Quick fact

In cancer, tumor suppressor genes like p16 and BRCA1 are often silenced by hypermethylation, acting like a 'molecular switch' that turns them off without any mutation.

Why this is interesting

Every cell in your body has the same DNA, yet a liver cell and a neuron look and act completely differently. So how can cancer hijack this system to switch genes on and off at will?