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Medicine

Targeted Therapy for BRAF-Mutant Melanoma

Quick fact

About half of all melanomas carry a BRAF V600E mutation, and targeted therapies can shrink tumors in most patients within weeks—but resistance usually develops within a year if used alone.

Why this is interesting

Imagine a cancer that can be turned off like a light switch—but only for a while. What happens when the cancer learns to turn the light back on?