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Medicine

Pneumocystis Jirovecii Pneumonia Prophylaxis in Immunocompromised Hosts

Quick fact

Trimethoprim-sulfamethoxazole (TMP-SMX) reduces the risk of Pneumocystis pneumonia by over 90% when used as prophylaxis in HIV patients with a CD4 count below 200 cells/µL.

Why this is interesting

You might think a fungus is the last thing you'd catch from the air you breathe every day—but for someone with a weakened immune system, that's exactly the danger of Pneumocystis jirovecii.