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Medicine

Perineural Invasion as a Prognostic Indicator in Squamous Cell Carcinoma

Quick fact

Perineural invasion in squamous cell carcinoma is an independent predictor of local recurrence, nodal metastasis, and reduced disease-specific survival, even after controlling for tumor size and depth.

Why this is interesting

A skin cancer that looks small and removable can still be deadly if it has silently spread along a nerve. What hidden sign reveals this aggressive potential?