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Medicine

Multidrug-Resistant Tuberculosis Treatment Regimens and Monitoring

Quick fact

Scientists have known for decades that multidrug-resistant tuberculosis requires a combination of second-line drugs, but it was only in 2019 that a new regimen, the 6-month bedaquiline/pretomanid/linezolid/moxifloxacin (BPaL) regimen, was shown to be as effective as longer therapies, curing about 90% of patients.

Why this is interesting

Imagine an infection that no longer responds to the strongest antibiotics we have—yet it can still be cured. How do doctors design a treatment when the standard fails?