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Chemistry

The Principles of Combinatorial Chemistry in Accelerating Drug Discovery

Quick fact

A single combinatorial synthesis using the 'split-and-pool' method can generate millions of distinct compounds in just a few days, whereas traditional sequential synthesis would take years to create the same number.

Why this is interesting

Imagine trying to find one key in a sea of millions—combinatorial chemistry hands chemists a master keyring with countless variations, all at once. How can this parallel approach dramatically speed up drug discovery?