Chemistry
How G Protein-Coupled Receptors Transmit Hormonal Signals into Cells
Quick fact
GPCRs are so important that about one-third of all FDA-approved drugs target them, making them the most successful drug target family in medicine.
Why this is interesting
You know that hormones like adrenaline trigger your 'fight-or-flight' response in seconds, but how does a single molecule outside a cell change the behavior of the whole cell? The answer lies in a remarkable class of proteins that sense the hormone and pass the message across the membrane.