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Biology

Pharmacogenomic Testing for CYP2D6 and Codeine Efficacy

Quick fact

About 7% of people are 'poor metabolizers' who cannot convert codeine into its active form, while up to 29% of some populations are 'ultrarapid metabolizers' who may produce life-threatening amounts of morphine.

Why this is interesting

Why does the same dose of codeine relieve pain in one person, but do nothing—or even cause dangerous side effects—in another? The answer lies in your DNA.