Medicine
Antiretroviral Therapy Simplification to Dual Regimens in HIV
Quick fact
For people who have been virally suppressed on a three-drug regimen for at least six months, switching to a two-drug regimen with dolutegravir and lamivudine can safely maintain viral suppression while reducing the risk of kidney and bone toxicity from tenofovir, a common third drug.
Why this is interesting
Most people with HIV take three drugs every day—but what if two could do the job just as well? Simplifying to a dual regimen is becoming a powerful way to reduce pill burden, side effects, and long-term toxicity.