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Chemistry

Basic Principles of X-ray Crystallography for Structure Determination

Quick fact

The first protein structure solved by X-ray crystallography was myoglobin in 1958, earning John Kendrew the Nobel Prize. Today, the method has determined over 150,000 molecular structures.

Why this is interesting

How can we 'see' individual atoms, which are far smaller than any microscope? X-ray crystallography uses the way atoms scatter X-rays to create a pattern that holds the secret to their arrangement.