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Chemistry

The Chemistry of Diaryliodonium Salts as Electrophilic Arylating Agents

Quick fact

Diaryliodonium salts can transfer an aryl group to nucleophiles such as amines, alcohols, and even carbon nucleophiles without the need for a transition-metal catalyst, often at room temperature. They owe this remarkable reactivity to the excellent leaving group ability of the iodobenzene moiety.

Why this is interesting

You've probably seen reactions that need a metal catalyst and a precious ligand to put an aryl group onto a molecule. But what if you could do it with just a simple salt, no metal required?