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Chemistry

The Role of Porphyrin Analogs in Photodynamic Inactivation of Bacteria

Quick fact

Porphyrin analogs can kill bacteria by generating singlet oxygen when exposed to visible light, a mechanism that attacks multiple cellular targets simultaneously, making it exceedingly difficult for bacteria to develop resistance.

Why this is interesting

We often think of antibiotics as the only way to kill bacteria—but what if we could simply shine a light on them to destroy even the most resistant strains?