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Chemistry

Chromatographic Separation of Chiral Compounds Using Polysaccharide-Based Stationary Phases

Quick fact

Polysaccharide-based stationary phases, derived from naturally abundant cellulose and amylose, are the most widely used chiral selectors for HPLC, accounting for over 90% of chiral separations in the pharmaceutical industry.

Why this is interesting

Have you ever wondered how the left-handed version of a drug can cure you while its mirror image is inactive—or worse, harmful? Chromatography can tell them apart, and the key might be in the cornstarch in your kitchen.