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Biology

Pain Pathways and Nociceptor Sensitization in Chronic Pain

Quick fact

Chronic pain affects over 20% of adults worldwide, and in many cases, the original tissue injury has healed—yet the brain still receives exaggerated pain signals because the nociceptors have become 'tuned' to fire more easily.

Why this is interesting

We all know pain is a warning signal, but why does it sometimes persist long after an injury has healed? What changes in the nervous system to turn a protective alarm into a chronic condition that seems to have no off switch?

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Pain Pathways and Nociceptor Sensitization in Chronic Pain

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