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Biology

T Cell Receptor Diversity Generated by VDJ Recombination

Quick fact

The combination of V, D, and J gene segments in T cell receptor genes can generate over 10^18 possible receptor sequences, far more than the number of T cells in your body, ensuring that nearly any pathogen can be recognized.

Why this is interesting

Your immune system can recognize billions of different threats, yet your genome has only about 20,000 genes. How does such a limited set of instructions produce such an incredible variety of T cell receptors?

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T Cell Receptor Diversity Generated by VDJ Recombination

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