Biology
Glomerular Basement Membrane Alterations in Nephrotic Syndrome
Quick fact
In nephrotic syndrome, the glomerular basement membrane thickens and becomes more porous, allowing large proteins like albumin to escape into the urine, causing the hallmark 'foamy urine'.
Why this is interesting
You know your kidneys filter blood, but what happens when the filter's basement membrane—the mesh that keeps proteins in—gets damaged? That's the story behind nephrotic syndrome.